Maciej S Lesniak Selected Research

Oncolytic Virotherapy

1/2021	Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma.
3/2019	Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer.
1/2018	Gene Therapy and Virotherapy of Gliomas.
7/2017	Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model.
6/2017	A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model.
1/2016	Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma.
11/2015	Stem Cell-Based Cell Carrier for Targeted Oncolytic Virotherapy: Translational Opportunity and Open Questions.
3/2015	Sui generis: gene therapy and delivery systems for the treatment of glioblastoma.
1/2015	Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy.
7/2013	Antiglioma oncolytic virotherapy: unattainable goal or a success story in the making?

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Maciej S Lesniak Research Topics

Disease

116	Neoplasms (Cancer) 01/2022 - 08/2002
91	Glioma (Gliomas) 01/2022 - 09/2005
65	Brain Neoplasms (Brain Tumor) 01/2022 - 08/2003
41	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 11/2005
12	Breast Neoplasms (Breast Cancer) 01/2022 - 02/2013
12	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2012
7	Melanoma (Melanoma, Malignant) 01/2021 - 11/2007
7	Infections 01/2020 - 05/2007
4	Hypoxia (Hypoxemia) 01/2022 - 01/2014
3	Carcinogenesis 11/2021 - 09/2006
3	Necrosis 01/2020 - 06/2015
3	Ischemia 08/2017 - 04/2014
2	Circulating Neoplastic Cells 02/2022 - 12/2019
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 12/2013
2	Virus Diseases (Viral Diseases) 01/2021 - 07/2013
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 01/2014
2	Ovarian Neoplasms (Ovarian Cancer) 03/2019 - 12/2013
2	Inflammation (Inflammations) 01/2019 - 08/2017
2	Triple Negative Breast Neoplasms 10/2018 - 02/2013
2	Hyperthermia 02/2016 - 06/2014
2	Lung Neoplasms (Lung Cancer) 12/2013 - 08/2011
2	Astrocytoma (Pilocytic Astrocytoma) 08/2011 - 06/2007
2	Pituitary Neoplasms (Pituitary Adenoma) 09/2006 - 09/2006

Drug/Important Bio-Agent (IBA)

18	Pharmaceutical PreparationsIBA 01/2022 - 08/2005
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2006
10	SurvivinIBA 01/2021 - 04/2006
9	CytokinesIBA 01/2021 - 08/2003
9	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 01/2011
8	AntigensIBA 01/2020 - 05/2006
7	Peptides (Polypeptides)IBA 01/2020 - 07/2007
7	EnzymesIBA 01/2020 - 06/2007
6	LigandsIBA 01/2020 - 07/2007
6	PolymersIBA 01/2019 - 08/2005
6	Messenger RNA (mRNA)IBA 04/2012 - 05/2007
5	Tryptophan (L-Tryptophan)FDA Link 01/2020 - 01/2013
5	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2019 - 11/2012
5	Therapeutic UsesIBA 01/2019 - 11/2011
4	AntibodiesIBA 01/2022 - 11/2014
4	Small Interfering RNA (siRNA)IBA 01/2022 - 03/2009
4	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2020 - 09/2009
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2016 - 09/2005
4	Antineoplastic Agents (Antineoplastics)IBA 01/2016 - 10/2010
4	LuciferasesIBA 07/2008 - 04/2006
3	human ERBB2 proteinIBA 01/2022 - 10/2015
3	Monoclonal AntibodiesIBA 01/2022 - 09/2006
3	Trastuzumab (Herceptin)FDA Link 01/2022 - 10/2015
3	Biological ProductsIBA 11/2021 - 11/2005
3	ChemokinesIBA 01/2021 - 12/2013
3	IntegrinsIBA 01/2019 - 03/2007
3	Retinaldehyde (Retinal)IBA 08/2017 - 04/2014
3	Neoplasm Antigens (Tumor Antigens)IBA 06/2017 - 05/2006
3	GoldIBA 01/2017 - 12/2014
3	Conditioned Culture MediaIBA 01/2016 - 04/2014
3	Carmustine (FIVB)FDA Link 01/2013 - 11/2005
3	epidermal growth factor receptor VIIIIBA 06/2010 - 12/2007
3	adenovirus receptorIBA 06/2009 - 09/2006
3	Interleukin-2 (IL2)IBA 09/2005 - 08/2003
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2019
2	tucatinibIBA 01/2022 - 10/2020
2	Ferrosoferric Oxide (Magnetite)FDA Link 12/2021 - 10/2013
2	InterleukinsIBA 01/2021 - 06/2010
2	Arginine (L-Arginine)FDA Link 01/2021 - 01/2014
2	antiglomerular basement membrane antibodyIBA 01/2021 - 01/2019
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2020 - 01/2019
2	TubulinIBA 01/2020 - 05/2015
2	ferric oxide (iron oxide)IBA 01/2020 - 06/2012
2	ZincIBA 01/2020 - 01/2017
2	MicroRNAs (MicroRNA)IBA 01/2020 - 01/2013
2	Chimeric Antigen ReceptorsIBA 01/2018 - 02/2016
2	Epidermal Growth Factor (EGF)IBA 01/2017 - 01/2017
2	VaccinesIBA 07/2015 - 12/2007
2	Heme Oxygenase-1IBA 01/2014 - 06/2007
2	MicellesIBA 01/2014 - 12/2013
2	Interleukin-13 Receptors (Interleukin 13 Receptor)IBA 08/2012 - 02/2007
2	CeramidesIBA 11/2010 - 02/2010
2	ElementsIBA 11/2007 - 05/2007
2	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 07/2007 - 03/2007
2	Coxsackie and Adenovirus Receptor-Like Membrane ProteinIBA 03/2007 - 05/2006
1	Circulating Tumor DNAIBA 02/2022
1	olfactomedinIBA 01/2022
1	taxaneIBA 01/2022
1	Antidepressive Agents (Antidepressants)IBA 01/2022
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2022
1	OsteopontinIBA 01/2022
1	OligodeoxyribonucleotidesIBA 01/2022
1	signal sequence receptorIBA 01/2022

Therapy/Procedure

91	Therapeutics 01/2022 - 08/2003
24	Immunotherapy 11/2021 - 10/2004
19	Drug Therapy (Chemotherapy) 01/2022 - 11/2005
15	Oncolytic Virotherapy 01/2021 - 05/2007
14	Radiotherapy 11/2019 - 04/2007
3	Intravenous Administration 01/2016 - 01/2014
2	Transplantation 01/2020 - 10/2013
2	Adjuvant Radiotherapy 01/2019 - 01/2018
2	Intravenous Injections 10/2018 - 10/2013
2	Chemoradiotherapy 01/2018 - 03/2015
2	Immunomodulation 10/2017 - 01/2010
2	Injections 04/2014 - 09/2006
2	Craniotomy 06/2010 - 09/2006